Supragenix cb-1

The cannabinoid receptor 1 (CB 1) is the principal target of the psychoactive constituent of marijuana, the partial agonist Δ 9-tetrahydrocannabinol (Δ 9-THC) 1.Here we report two agonist-bound crystal structures of human CB 1 in complex with a tetrahydrocannabinol (AM11542) and a hexahydrocannabinol (AM841) at 2.80 Å and 2.95 Å resolution, respectively..

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